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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
21.52
Human Site:
T514
Identified Species:
36.41
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T514
Q
M
N
I
D
V
A
T
W
V
R
L
L
R
R
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T741
Q
M
N
I
D
V
A
T
W
V
R
L
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
A566
Q
M
N
L
S
M
A
A
W
G
R
L
V
M
N
Dog
Lupus familis
XP_542019
1076
118222
T647
Q
M
N
I
D
V
A
T
W
V
R
L
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
T517
Q
M
N
I
D
V
A
T
W
V
R
L
L
R
R
Rat
Rattus norvegicus
Q63433
946
104449
T517
Q
M
N
I
D
V
A
T
W
V
R
L
L
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
T554
Q
M
N
I
N
I
V
T
W
G
R
L
V
L
G
Chicken
Gallus gallus
XP_422357
1013
114806
I538
L
R
A
P
Q
M
N
I
N
I
A
T
W
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
V523
L
R
A
R
Q
M
N
V
D
I
G
T
F
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
A240
N
Y
G
A
S
L
G
A
D
G
D
G
A
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G313
A
A
E
L
A
Q
L
G
L
T
G
D
K
M
S
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
R374
R
P
R
P
P
I
Q
R
L
S
F
G
E
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
K699
R
D
E
L
E
L
W
K
A
Q
R
E
E
M
E
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A672
T
S
S
T
T
A
S
A
A
A
A
A
A
M
A
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
46.6
100
N.A.
100
100
N.A.
53.3
6.6
N.A.
6.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
73.3
20
N.A.
20
N.A.
6.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
8
8
43
22
15
8
15
8
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
36
0
0
0
15
0
8
8
0
0
8
% D
% Glu:
0
0
15
0
8
0
0
0
0
0
0
8
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
8
8
0
22
15
15
0
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
43
0
15
0
8
0
15
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% K
% Leu:
15
0
0
22
0
15
8
0
15
0
0
50
36
8
0
% L
% Met:
0
50
0
0
0
22
0
0
0
0
0
0
0
29
0
% M
% Asn:
8
0
50
0
8
0
15
0
8
0
0
0
0
0
8
% N
% Pro:
0
8
0
15
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
50
0
0
0
15
8
8
0
0
8
0
0
0
0
0
% Q
% Arg:
15
15
8
8
0
0
0
8
0
0
58
0
0
36
50
% R
% Ser:
0
8
8
0
15
0
8
0
0
8
0
0
0
0
8
% S
% Thr:
8
0
0
8
8
0
0
43
0
8
0
15
0
0
0
% T
% Val:
0
0
0
0
0
36
8
8
0
36
0
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
50
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _